Thursday, March 24, 2016

Nimesulide tablet actions and uses


Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) which acts as a cyclooxygenase- 2 inhibitor. It has become a leading NSAID in over 50 countries worldwide.
Nimesulide tablet is used for the treatment of osteoarthritis, postoperative trauma, sports injuries, acute musculoskeletal disorders including tendonitis, tenosynovitis, sprains, strains and low back pain, ear, nose and throat disorders.
Nimesulide tablet undergoes extensive biotransformation and has a relatively rapid onset of action, with meaningful reductions in pain and inflammation observed within 15 minutes from drug intake.
Its an anti-inflammatory with analgesic and antipyretic activity. It is also has low gastro-intestinal and renal toxicity.
Its multifactorial mode of action gives a unique and broad action on inflammatory processes.
Additionally it helps in increasing energy, improve skin tone, and to cure Heart diseases, and also helpful for dry skin.
It is used for treatment of all types of pains resulting from sports injury, depression  etc.

Nimesulide Dose and duration for the treatment


The most prescribed Non-steroidal Anti-inflammatory pain killer drug- Nimesulide was launched in Italy for the first time as Aulin and Mesulid in 1985 and is presently available in more than 50 countries worldwide with different trademarks.
The tablet is used for the treatment of post-traumatic inflammation, acute musculoskeletal disorders including sprains, strains, tendinitis, tenosynovitis, low back pain, periarthritis (shoulder pain) and osteoarthritis (joint pains), stiffness.
The maximum duration and dose of a treatment course with Nimesulide medicine is 15 days, 100 mg twice a day, to minimize the risk of hepatotoxicity.
 It also preffered to use for the age above 12.
Women should use the drug with caution during lactation and it is contraindicated during pregnancy.

Nise gel for pain relief


Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) with analgesic (pain relief) and antipyretic (reduction of body temperature) properties.
Nimesulide is available in the market world wide over 50 countries with different trademarks.
Nise is a trademark for the tablet Nimesulide which is a Non-steroidal medicinal drug (NSAIDs) and is available in the form of tablets, capsule, and Gel.
Nise Gel is used to treat chronic and acute musculoskeletal disorders such as soft tissue injuries or non-articular rheumatic disorders, including discomfort in the muscles, tendonitis, back pain/ache, arthritis, tenosynovitis sprains, or strains.
Nise Gel (Nimesulide/Methyl Salicylate/Menthol/Capsaicin) is used topically. It is prescribed to apply to the affected area, rubbing in a thin layer of the gel 2 to 4 times every day.
The dose needed to be applied is three to four times per day depending on the dimension of the affected size and response. Medicalcare ought to be reviewed after 4 weeks.
It should not be apply near mouth, eyes, nose, genitals, or on any damaged skin, cut, open sores, or sun burnt skin.

Wednesday, February 10, 2016

Nimesulide advantages


The most powerfull painkiller NSAIDs tablet Nimesulide is been available since 1985 and authorised in worldwide over 50 countries.
It has superior gastrointestinal safety as compared to other NSAIDs.
It is available in various forms apart from tablets such as in the form of Gell, powder, and suppositories. It’s also available in several trademarks.
Nimesulide brands such as Sulide, Nimalox, Nimesil, Nimulid, Nicip, Nimcap, Nise, Sulidene and Zolan.
Nimulid is also obtaining in the form of gel.
The Nimulid Transgel a brand from Nimesulide Transdermal Gel is indicated for post-traumatic inflammation, acute musculoskeletal disorders including sprains, strains, tendinitis, tenosynovitis, low back pain, periarthritis (shoulder pain) and osteoarthritis (joint pains), stiffness.
Nimesulide Advantages
Nimesulide is an NSAID and a preferential COX II inhibitor. It is a potent analgesic, antipyretic, and potent Anti-Inflammatory action.
It behaves as a competetive inhibitor of histamine release in-vivo and in-vitro, hence posseses antihistaminic and antiallergic properties.
It has superior gastrointestinal safety as compared to other NSAIDs.
Its multifactorial mode of action gives it a unique and broad action on inflammatory processes.

Nimesulide formulation


Nimesulide, a widely prescribed anti-inflammatory analgesic drug belongs to BCS class II and exhibit low and variable oral bioavailability.

Nimesulide (4-nitro-2-phenoxymethanesulfoanilide) may be a particular Cox-2 anti-inflammatory medication. This compound, a by-result of p-nitrophenyl methane arrangement sulfa, is structurally a solitary non-steroidal anti-inflammatory drug. It has a place with particular COX-2inhibitors, with an intense pain relieving movement.
its shown as second line treatment for  acute pain, symptomatic treatment of excruciating degenerative joint ailment and first dysmenorrhoea.
The main purpose of Nimesulide tablets is for the treatment of painful inflammatory conditions, back pain, dysmenorrhea, postoperative pain, osteoarthritis, and fever.

Additionally it also helps to reduce cancer and heart problem. It is also used for dry skin, to improve skin-tone,and to increase energy.
Nimesulide tablet incorporates:
  • Fast results
  • Helpful and supportive
  • No feature impacts
  • Fast and quick effects
Nimesulide Tablet Advantages:
  • Nimesulide has less gastrointestinal adverse effects than other NSAIDs
  • It has superior benefit-risk ratio to other drugs with a comparable safety and tolerability to placebo.
  • Its multifactorial mode of action gives it a unique and broad action on inflammatory.
  • Nimesulide is also safe in sensitive asthmatic patients. It is reported to be beneficial in relieving the symptoms of rhinitis, rhinopharyngitis tubaritis and seceretory otitis media with concomitant antibiotic treatment.

Nimesulide combination


The generic Nimesulide combination is manufactured by 399 companies and has nearly 522 Brands of Generics of Nimesulide.
Nimesulide is a Non steroidal anti inflammatory drug (NSAID) and targets COX-2 an enzyme responsible for inflammation & pain.
The Nimesulide is preferably used in the composition in an amount of 0.1-5% by weight, more preferably in an amount of 0.1-3% by weight, most preferably in an amount of around 1 % by weight of the composition.
Some of brands of Nimesulide are:
Nepar – Nimuselide 100 mg + Paracetamol 500 mg
Nimular Plus – Nimesulide, Acetaminophen
Nipar (100 mg) – Nimesulide, Paracetamol
Abinim-P – Nimesulide 100 mg, paracetamol 500 mg.
Nimesulide is distributed world-wide through a network of selected international partners.
Nimesulide is mainly used for the treatment of:
Back Pain
Dysmenorrhea
Osteoarthritis
Rheumatoid Arthritis
Nimesulide is always recommended to use under a licensed physician supervision

Saturday, February 6, 2016

Nimesulide pill


Nimesulide is a recently developed analgesic, antipyretic and anti-inflammatory agent that differs from conventional nonsteroidal anti-inflammatory drugs both in structure and pharmacological profile. Since nimesulide may be prescribed for patients receiving concomitant medication, the propensity for drug interactions exists.
Major interactions involving interference with drug metabolism have not been described with Nimesulide.
Its main purpose is to treat acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea .
Nimesulide Tablet shows the result from pain within 15min from the drug intake
Nimesulide is available in the from of tablet, capsule and gel with the dosage of 100mg
Nimesulide is preffered for the shortest duration to minimize the risk of hepatotoxicity.
A non-steroidal anti-inflammatory most prescribed drug – Nimesulide that contains dose of 100mg and it’s used for treating acute (short-term) pain, painful osteoarthritis (swelling in the joints), and Primary dysmennorhea (Period Pains).
Nimesuilde is first launched in 1985and currently it’s on the market in worldwide of over 50 countries as orginal product with the trademarks of Nise, Nimopen-MP, Nic-Spas, Nimulid, Nicip, e.t.c.