Nimesulide advantages

The most powerfull painkiller NSAIDs tablet Nimesulide is been available since 1985 and authorised in worldwide over 50 countries.

It has superior gastrointestinal safety as compared to other NSAIDs.

It is available in various forms apart from tablets such as in the form of Gell, powder, and suppositories. It’s also available in several trademarks.

Nimesulide brands such as Sulide, Nimalox, Nimesil, Nimulid, Nicip, Nimcap, Nise, Sulidene and Zolan.

Nimulid is also obtaining in the form of gel.

The Nimulid Transgel a brand from Nimesulide Transdermal Gel is indicated for post-traumatic inflammation, acute musculoskeletal disorders including sprains, strains, tendinitis, tenosynovitis, low back pain, periarthritis (shoulder pain) and osteoarthritis (joint pains), stiffness.

Nimesulide Advantages
Nimesulide is an NSAID and a preferential COX II inhibitor. It is a potent analgesic, antipyretic, and potent Anti-Inflammatory action.

It behaves as a competetive inhibitor of histamine release in-vivo and in-vitro, hence posseses antihistaminic and antiallergic properties.

It has superior gastrointestinal safety as compared to other NSAIDs.

Its multifactorial mode of action gives it a unique and broad action on inflammatory processes.

Nimesulide formulation

Nimesulide, a widely prescribed anti-inflammatory analgesic drug belongs to BCS class II and exhibit low and variable oral bioavailability.

Nimesulide (4-nitro-2-phenoxymethanesulfoanilide) may be a particular Cox-2 anti-inflammatory medication. This compound, a by-result of p-nitrophenyl methane arrangement sulfa, is structurally a solitary non-steroidal anti-inflammatory drug. It has a place with particular COX-2inhibitors, with an intense pain relieving movement.

its shown as second line treatment for  acute pain, symptomatic treatment of excruciating degenerative joint ailment and first dysmenorrhoea.

The main purpose of Nimesulide tablets is for the treatment of painful inflammatory conditions, back pain, dysmenorrhea, postoperative pain, osteoarthritis, and fever.

Additionally it also helps to reduce cancer and heart problem. It is also used for dry skin, to improve skin-tone,and to increase energy.

Nimesulide tablet incorporates:

• Fast results
• Helpful and supportive
• No feature impacts
• Fast and quick effects

Nimesulide Tablet Advantages:

• Nimesulide has less gastrointestinal adverse effects than other NSAIDs
• It has superior benefit-risk ratio to other drugs with a comparable safety and tolerability to placebo.
• Its multifactorial mode of action gives it a unique and broad action on inflammatory.
• Nimesulide is also safe in sensitive asthmatic patients. It is reported to be beneficial in relieving the symptoms of rhinitis, rhinopharyngitis tubaritis and seceretory otitis media with concomitant antibiotic treatment.

Nimesulide combination

The generic Nimesulide combination is manufactured by 399 companies and has nearly 522 Brands of Generics of Nimesulide.

Nimesulide is a Non steroidal anti inflammatory drug (NSAID) and targets COX-2 an enzyme responsible for inflammation & pain.

The Nimesulide is preferably used in the composition in an amount of 0.1-5% by weight, more preferably in an amount of 0.1-3% by weight, most preferably in an amount of around 1 % by weight of the composition.

Some of brands of Nimesulide are:
Nepar – Nimuselide 100 mg + Paracetamol 500 mg
Nimular Plus – Nimesulide, Acetaminophen
Nipar (100 mg) – Nimesulide, Paracetamol
Abinim-P – Nimesulide 100 mg, paracetamol 500 mg.
Nimesulide is distributed world-wide through a network of selected international partners.

Nimesulide is mainly used for the treatment of:
Back Pain
Dysmenorrhea
Osteoarthritis
Rheumatoid Arthritis
Nimesulide is always recommended to use under a licensed physician supervision

Nimesulide pill

Nimesulide is a recently developed analgesic, antipyretic and anti-inflammatory agent that differs from conventional nonsteroidal anti-inflammatory drugs both in structure and pharmacological profile. Since nimesulide may be prescribed for patients receiving concomitant medication, the propensity for drug interactions exists.

Major interactions involving interference with drug metabolism have not been described with Nimesulide.

Its main purpose is to treat acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea .

Nimesulide Tablet shows the result from pain within 15min from the drug intake
Nimesulide is available in the from of tablet, capsule and gel with the dosage of 100mg
Nimesulide is preffered for the shortest duration to minimize the risk of hepatotoxicity.

A non-steroidal anti-inflammatory most prescribed drug – Nimesulide that contains dose of 100mg and it’s used for treating acute (short-term) pain, painful osteoarthritis (swelling in the joints), and Primary dysmennorhea (Period Pains).

Nimesuilde is first launched in 1985and currently it’s on the market in worldwide of over 50 countries as orginal product with the trademarks of Nise, Nimopen-MP, Nic-Spas, Nimulid, Nicip, e.t.c.

Nimesulide synthesis

Nimesulide is a non-steroidal anti-inflammatory agent that is generally utilized as a part of the treatment of inflammatory torment which hinders the protein cyclooxygenase-2 (COX-2) and has better gastro-intestinal mediocrity in addition to different NSAIDs in its class.

Its approved signs are the treatment of intense torment, the symptomatic treatment of osteoarthritis and essential dysmenorrhoea, sports wounds and so on.

Its binding conformation and interaction mode were studied with molecular docking experiments. Compound 20f could become a lead compound for further development for potential anti-inflammatory drugs.

Clinically it has demonstrated that it supports an especially good profile as far as gastrointestinal tolerabilityNimesulide is a COX-2 selective drug which has the properties of antiinflammatory and antihistaminic, it also possesses analgesic properties.

Apart for the treatment of acute pain, osteoarthritis and primary dysmenorrhoea. Nimesulide is also being widely used for anticancer and antiviral agents.

A variety of new nimesulide derivatives were synthesized through incorporation of a 5-LOX pharmacophore into Nimesulide followed with some structural modifications. which were then characterized for dual enzyme inhibitors for these two types of enzymes (Cyclooxygenase-½ (COX-½) and 5-lipoxygenase (5-LOX) )

Nimesulide is available in various forms like powder/granules, gel, and suppositories.

Clinically it has proven that it supports a particularly good profile in terms of gastrointestinal tolerability.

Nimesulide drug interactions

Nimesulide is a recently developed analgesic, antipyretic and anti-inflammatory agent that differs from conventional nonsteroidal anti-inflammatory drugs both in structure and pharmacological profile. Since nimesulide may be prescribed for patients receiving concomitant medication, the propensity for drug interactions exists.

Major interactions involving interference with drug metabolism have not been described with Nimesulide.

A marginal decrease in plasma theophylline levels (without changes in respiratory function tests) has been described after addition of Nimesulide to chronic theophylline therapy. Nimesulide is available in the market with the dosage of 100mg.

Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults.

it’s an ethical medicine suggested to use medicine beneath authorised physician supervision.

Nimesulide is also available in the form of dissolving tablets, granules for oral suspension, and Gel. The fast dissolving tablets of Nimesulide contains superdisintegrants, which accelerates the disintegration of tablets by virtue of their ability to absorb large amount of water when exposed to aqueous environment.

Nimesulide granules

Nimesulide Granules is non-steroidal anti-inflammatory drugs, indicated for the treatment of juvenile chronic arthritis, postoperative pain, acute pain after trauma and primary dysmenorrhea.

Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties.

Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old.

Active ingredients: nimodipine. Indication: nimesulide granules is non-steroidal anti-inflammatory drugs, indicated for the treatment of juvenile chronic arthritis, postoperative pain, acute pain after trauma and primary dysmenorrhea.

Packaging: 1g / sack; 6, 8, 10 sacks / pack. Contact us for more information.

usage and consumption: oral, the goods only for adults only, a 50 mg to 100 mg daily twice postprandial taking. In accordance with the severity of the conditions and the needs of the patients can be increased to 0.2g, the second service.

elderly patients of the medication should strictly comply with the provisions of doctors. Doctors can reduce under appropriate in the circumstances listed above dosage.